This course will be a comprehensive update of issues in hematologic and oncologic malignancies presenting new disease classification, treatment, and challenging cases. Course topics will include updates from the American Society of Hematology (ASH) annual meeting and in medical oncology. Topics focus on key hematologic diseases (dysproteinemias, acute and chronic leukemias, lymphomas), key solid tumors (breast, thoracic, GI, GU), and overlap topics of supportive, ancillary and diagnostic care. Important recent advances in managing breast, genitourinary, gastrointestinal and thoracic malignancies will also be discussed. The course offers challenging and interactive sessions on pertinent issues involved with the care of patients.