January 23 - 25 2015, 12:00 AM - 12:00 AM


February 07 - 08 2015, 12:00 AM - 12:00 AM

ASA Certificate in Business Administration 2015

June 26 - 28 2015, 12:00 AM - 12:00 AM

Annual Perioperative Surgical Home Summit



November 21, 2014

FDA MedWatch - Respironics California, Esprit V1000 and V200 Ventilators: Class I Recall - Power Failure May Occur


FDA MedWatch Respironics California Esprit V1000 and V200 Ventilators Class I Recall

November 07, 2014

FDA MedWatch - Nellcor Puritan Bennett, 980 Ventilator System: Class I Recall - Software Issue May Stop Ventilator


FDA MedWatch Nellcor Puritan Bennett 980 Ventilator System Class I Recall

October 25, 2014

FDA MedWatch - Intravia Containers by Baxter: Recall - Particulate Matter


FDA MedWatch Intravia Containers by Baxter Recall



Add this product to your shopping cart

Self-Education and Evaluation (SEE) Program

SKU: 30701-14CE

... Read more »

Single Copies, Member Price: $360

Chronic Statin Therapy Associated With Reduced Postoperative Mortality

Chicago — (December 22, 2010) 

Statin drugs were first introduced to lower blood cholesterol concentrations; however, research is now discovering other benefits. A new study from France, published in the January 2011 issue of Anesthesiology, is the first to analyze the impact of preoperative chronic statin therapy on postoperative adverse events in surgical patients. Findings from the study suggest that statin therapy is associated with reduced postoperative mortality.

"Preoperative uses of statins have demonstrated major cardiac and non-cardiac protective effects, including in this study. Since we are now able to also understand the postoperative effects of statin therapy, it should be considered as a global protection for patients," said study author, Bruno Riou, M.D., Ph.D.

The observational study analyzed 1,674 patients undergoing aortic reconstruction surgeries from January 2001 to December 2009. Researchers from the Université Pierre et Marie Curie (UPMC) and the Assistance Publique-Hôpitaux de Paris in Paris, France, compared the outcomes between patients who received chronic statin therapy with those who did not. Results showed statins were associated with the following:

  • An almost threefold reduction in the risk of death in patients undergoing major vascular surgery.
  • An almost twofold reduction in the risk of postoperative heart attack.
  • A reduced risk of postoperative stroke and kidney failure.

While statins did not reduce the risk of pneumonia, multiple organ dysfunction syndrome, and surgical complications, they did reduce mortality in patients with postoperative multiple organ dysfunction syndrome and in those developing postoperative surgical complications.

Lead study author Yannick Le Manach, M.D. added that his research team believes the way statins are currently administered to patients remains a limitation. He supports the development of intravenous formulations of statins in order to administer the drugs during and immediately after surgery. This could improve postoperative outcomes by maintaining optimal blood concentrations and avoiding low plasma levels.

For more information, visit the Anesthesiology website at www.anesthesiology.org.


Founded in 1905, the American Society of Anesthesiologists (ASA) is an educational, research and scientific society with more than 52,000 members organized to raise and maintain the standards of the medical practice of anesthesiology. ASA is committed to ensuring physician anesthesiologists evaluate and supervise the medical care of patients before, during and after surgery to provide the highest quality and safest care every patient deserves.

For more information on the field of anesthesiology, visit the American Society of Anesthesiologists online at asahq.org . To learn more about the role physician anesthesiologists play in ensuring patient safety, visit asahq.org/WhenSecondsCount. Like ASA on Facebook , follow ASALifeline on Twitter and follow ASA on LinkedIn .



American Society of Anesthesiologists