>

MEETINGS / EVENTS

RSS

November 08 - 09 2014, 12:00 AM - 12:00 AM

ASA Quality Meeting 2014

January 23 - 25 2015, 12:00 AM - 12:00 AM

ASA PRACTICE MANAGEMENT 2015

February 07 - 08 2015, 12:00 AM - 12:00 AM

ASA Certificate in Business Administration 2015

>

FDA MEDWATCH ALERTS

October 16, 2014

FDA MedWatch - LifeCare Flexible Intravenous Solutions by Hospira, Inc.: Recall - Potential for Leakage

Summary:

FDA MedWatch LifeCare Flexible Intravenous Solutions by Hospira Inc

October 13, 2014

FDA MedWatch - CareFusion EnVe and ReVel Ventilators: Class 1 Recall - Power Connection Failure

Summary:

FDA MedWatch CareFusion EnVe and ReVel Ventilators

October 13, 2014

FDA MedWatch - ICU Medical ConMed Stat2 Flow Controller: Class 1 Recall - Delivers Higher Flow Rate than Intended

Summary:

FDA MedWatch ICU Medical ConMed Stat2 Flow Controller

>

ASA FEATURED PRODUCT

Add this product to your shopping cart

Self-Education and Evaluation (SEE) Program

SKU: 30701-14CE

... Read more »

Single Copies, Member Price: $360

Study Finds That, for Obese Children, Less is More When it Comes to General Anesthesia

Chicago — (October 17, 2011) 

A study presented at ANESTHESIOLOGY 2011 this week found that obese children required much smaller doses of the anesthetic propofol than non-obese children to bring about a safe level of unconsciousness.

Since the commonly used drug propofol can cause low blood pressure, prolonged sleepiness and decreased breathing, the results of this study could help anesthesiologists safely treat a common, but often misunderstood, type of surgical patient.

“Little information is available to assist anesthesiologists in deciding the right amount of medication to give to an obese child,” said lead study author Olutoyin A. Olutoye, M.D., M.Sc., FAAP from the Texas Children’s Hospital in Houston. “Companies making these medications do not specifically study medication effects in this group of children before releasing a drug for use.”

It is therefore important for anesthesiologists to decide whether anesthetic drug doses should be based on a child’s actual weight or lean body weight. In obese children, 75 percent of excess body weight consists of fat tissue, which alters drug distribution.

“It is known that obese adults often need a smaller dose of propofol than normal weight adults, but a correlation to children is not guaranteed since adults and kids handle medications differently,” said Dr. Olutoye.

Using a process called the biased coin design, which requires fewer patients and provides more accurate calculation of dose requirements than older techniques, 40 obese and 40 non-obese children were studied.

After measuring each child’s response 20 seconds after receiving propofol, it was determined that obese children needed 2 mg/kg of propofol to bring about unconsciousness at the beginning of surgery, compared to normal weight children who needed 50-60 percent more propofol (3.2mg/kg).

“These study findings mean that when providing care for obese children with propofol, 95 percent of children will likely need only a smaller dose of propofol to initiate anesthesia for surgical procedures,” said Dr. Olutoye. “This is important as propofol may cause low blood pressure, an effect that can be worsened if larger-than-needed amounts are given.”

Dr. Olutoye stated that further pediatric studies will be needed to learn if there are other differences in medication responses for obese and non-obese children in clinical practice.

THE AMERICAN SOCIETY OF ANESTHESIOLOGISTS

Founded in 1905, the American Society of Anesthesiologists (ASA) is an educational, research and scientific society with more than 52,000 members organized to raise and maintain the standards of the medical practice of anesthesiology. ASA is committed to ensuring physician anesthesiologists evaluate and supervise the medical care of patients before, during and after surgery to provide the highest quality and safest care every patient deserves.

For more information on the field of anesthesiology, visit the American Society of Anesthesiologists online at asahq.org. To learn more about the role physician anesthesiologists play in ensuring patient safety, visit asahq.org/WhenSecondsCount. Join the ANESTHESIOLOGYTM 2014 social conversation today. Like ASA on Facebook, follow ASALifeline on Twitter and use the hashtag #ANES2014.

###

Contact:

American Society of Anesthesiologists
pr@asahq.org
847-825-5586